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Respiratory acidosis is a state in which there is usually a failure of ventilation and an accumulation of carbon dioxide. The primary disturbance of elevated arterial PCO2 is the decreased ratio of arterial bicarbonate to arterial PCO2, which leads to a lowering of the pH. In the presence of alveolar hypoventilation, 2 features commonly are ...May 1, 2023 · Corticosteroids are drugs used in the management and treatment of almost all areas of medicine. This activity outlines the indications, action, and contraindications for corticosteroids as a valuable agent in managing numerous disorders. This activity will highlight the mechanism of action, adverse side effects profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics ...In a way, history of wound care is the history of humankind. Well before any written historical record, chronic wounds of all shapes and sizes have plagued patients and created a significant burden on their caretakers. It has long been noticed that some patient factors are more likely to be associated with better wound healing [1][2][3]. Likewise, certain wound types have been noted to be ...Swyer-James-MacLeod syndrome (SJMS), also known as Swyer-James syndrome or hyperlucent lung syndrome, is an uncommon syndrome of unilateral functional hypoplasia of the pulmonary vasculature and emphysema, with or without associated bronchiectasis. The condition was first described simultaneously in the 1950s by a respiratory physician William ...Jul 25, 2023 · As a result, pursed-lip breathing helps support breathing by the opening of the airways during exhalation and increasing excretion of volatile acids in the form of carbon dioxide preventing or relieving hypercapnia. Through purse-lip breathing, people can have relief of shortness of breath, decrease the work of breathing, and improve gas exchange.In the early nineteenth century, Charles Dickens reported in his book "The Posthumous Papers of the Pickwick Club" on the obesity hypoventilation syndrome (OHS), which is defined as alveolar hypoventilation in an obese individual during wakefulness that cannot be explained to other conditions that lead to hypercapnia such as chronic obstructive lung disease (COPD).[1] OHS is linked to ...A lung abscess is a microbial infection of the lung that results in necrosis of the pulmonary parenchyma. It is classified as acute (less than four weeks) or chronic (more than four weeks) depending on the duration. Based on their etiology, they can be classified as primary, if they occur in the absence of underlying pulmonary lesions or secondary if they occur in the presence of underlying ...May 1, 2023 · Wheezing is the symptomatic manifestation of any disease process that causes airway obstruction. Rene Laennec's development of the stethoscope in 1816 has enabled a better appreciation of wheeze at the bedside, in comparison to the previously established practice of ear-to-chest auscultation. Wheeze is a musical, high-pitched, adventitious sound generated anywhere from the larynx to the distal ...Amlodipine, an oral dihydropyridine calcium channel blocker, demonstrates prolonged efficacy by inhibiting voltage-dependent L-type calcium channels. This action interrupts initial calcium influx, distinguishing it within its pharmacological class. With a half-life of 30 to 50 hours, amlodipine affords the convenience of once-daily dosing, …Dyspnea, commonly referred to as shortness of breath, is the subjective sensation of uncomfortable breathing comprised of various sensations of varying intensity. It is a common symptom impacting millions of people and maybe the primary manifestation respiratory, cardiac, neuromuscular, psychogenic, systemic illness, or a combination of …Sarcoidosis is a multisystem disorder of unknown etiology that mostly affects young adults worldwide and presents with noncaseating granulomas in various organs. Characteristically, it presents with bilateral hilar lymphadenopathy and reticular opacities in the lungs. Other major involved sites include skin, eyes, and joints. …Ipratropium is a bronchodilator medication that dilates the airways of the lungs. Ipratropium has been approved by the US Food and Drug Administration (FDA) for treating bronchospasms associated with chronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis. Maintenance therapy with ipratropium has established benefits in the treatment of COPD.StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. StatPearls [Internet]. Show details ... The reported incidence of tracheobronchomalacia in individuals suffering from COPD is 7 to 15%. Mounier-Kuhn syndrome is a rare disorder, as only approximately 300 cases have been reported to date. ...The measurement of carbon dioxide (CO2) was first developed in the early 1900s; however, it was complex and of limited clinical use.[1] On the most basic level, end-tidal CO2 (ETCO2) detectors are used to measure the exhaled concentration of carbon dioxide. The concentration of exhaled CO2 correlates to the arterial concentration of CO2, although multiple factors can impact the relationship ...Asbestosis is an interstitial lung disease caused by inhaling asbestos fibers (See Image. X-ray, Lungs, Asbestos, Anterior View). These fibers are mineral silicates (mainly hydrated magnesium silicates) and are classified into 2 main categories based on their shape: serpentine and amphibole.[1] Serpentine fibers include curly and flexible chrysolites and are less pathogenic than amphibole ...Pulmonary function tests (PFTs) allow physicians to evaluate the respiratory function of their patients in many clinical situations and when there are risk factors for lung disease, occupational exposures, and pulmonary toxicity. National guidelines for the measurements and interpretation of PFT are regularly updated, and the most recent guidelines developed by the international joint Task ...COPD Assessment Test (CAT)] - StatPearls - NCBI Bookshelf. Table 2. COPD Assessment Test (CAT) Used with Permission from 2020, Global Initiative for Chronic Obstructive Lung Disease (GOLD), available from www.goldcopd.org, published in Fontana, WI, USA. From: Chronic Obstructive Pulmonary Disease.Pulmonary edema is the accumulation of excessive fluid in the alveolar walls and alveolar spaces of the lungs. It can be a life-threatening condition in some patients with high mortality and requires immediate assessment and management. This activity reviews the pathophysiology, clinical presentation, evaluation, and management of cardiogenic ...Spirometry is one of the most readily available and useful tests for pulmonary function. It measures the volume of air exhaled at specific time points during complete exhalation by force, which is preceded by a maximal inhalation. The most important variables reported include total exhaled volume, known as the forced vital capacity (FVC), the ...PDF | On Oct 24, 2018, Parul Pahal and others published StatPearls [Internet]. Chronic Obstructive Pulmonary Disease (COPD), Compensatory Measure | Find, read and cite all the research you need on ...Chronic obstructive pulmonary disease (COPD) is a serious lung disease that usually affects older adults. Trusted Health Information from the National Institutes of Health Chronic ...Beta-2 adrenergic agonists are a drug class used as a mainstay treatment for respiratory diseases such as bronchial asthma and chronic obstructive pulmonary disease (COPD). They replicate the functions of catecholamines such as epinephrine, norepinephrine, and dopamine in producing different autonomic responses within the body. Specifically, the smooth muscle of the airway, uterus, intestine ...Epinephrine is one of the most commonly used agents in various settings as it functions as medication and hormone. It is currently FDA-approved for various situations, including emergency treatment of type 1 hypersensitivity reactions, including anaphylaxis, induction, and maintenance of mydriasis during intraocular surgeries and hypotension …Study Guide from StatPearls Publishing, Treasure Island (FL), 01 Mar 2018 PMID: 29489292 . Books ... Abstract . Pulmonary emphysema, a progressive lung disease, is a form of chronic obstructive pulmonary disease (COPD). The Global Initiative for chronic obstructive lung disease (GOLD) has defined COPD as "a common, preventable, and …A pulmonary embolism (PE) occurs when a blood clot obstructs the pulmonary artery or its branches. In deep vein thrombosis (DVT), a thrombus develops within the deep veins, most commonly in the lower extremities. PE usually occurs when a part of this thrombus breaks off and enters the pulmonary circulation. PE rarely occurs from the embolization of other materials into the pulmonary ...Towing monitoring systems are essential for towing. Learn more about towing monitoring systems at HowStuffWorks. Advertisement Modern automobiles contain an amazing number of elect...Obstructive sleep apnea (OSA) is characterized by episodes of a complete (apnea) or partial collapse (hypopnea) of the upper airway with an associated decrease in oxygen saturation or arousal from sleep.[1] This disturbance results in fragmented, nonrestorative sleep. Other symptoms include loud, disruptive snoring, witnessed apneas during sleep, and excessive daytime sleepiness.[2][3][4] OSA ...As a result, pursed-lip breathing helps support breathing by the opening of the airways during exhalation and increasing excretion of volatile acids in the form of carbon dioxide preventing or relieving hypercapnia. Through purse-lip breathing, people can have relief of shortness of breath, decrease the work of breathing, and improve gas exchange.An umbrella term used to describe different types of progressive lung diseases is known as Chronic Obstructive Pulmonary Disease (COPD). These are chronic infla An umbrella term us...Pleurisy is a symptom characterized by localized chest pain caused by a disease-causing inflammation of the pleura. Pleurisy can be caused by a primary pleural disease or secondary to a systemic illness. Hippocrates first described "pleuritis" in the 5 century B.C. as "pain in his side, fever and shivering" accompanied by "orthopnea" and …StatPearls offers bundled packages to everyone from large hospital systems to individual practices. Large colleges and universities as well as individual classrooms use our suite of healthcare educational and point-of-care resources. Our Learning Management System is incredibly flexible, and we offer unlimited access at very competitive pricing.Chronic obstructive pulmonary disease (COPD) is a common co-morbidity and cause of new complaints. Rapid recognition, assessment, and treatment are paramount to patient outcomes. Gone are the days of definitive airway management as first-line therapy.Boyle's law is a gas law that describes the relationship between the pressure and volume of gas for a mass and temperature. This law is the mechanism by which the human respiratory system functions. Boyle's law is equivalent to PV = K (P is pressure, V is volume, K is a constant), or one may state that pressure is inversely proportional to the volume.[1]Multifocal atrial tachycardia (MAT) is a supraventricular tachycardia with a rapid, irregular atrial rhythm arising from multiple ectopic foci within the atria. This arrhythmia is characterized by a heart rate of greater than 100 beats per minute with organized atrial activity yielding three or more different non-sinus P-wave morphologies in the same lead. There are irregular PP intervals and ...Respiratory failure can be classified based on chronicity (i.e., acute, chronic, and acute on chronic). A thorough understanding of respiratory failure is crucial to managing this disorder. If either type of respiratory failure is not identified and addressed early, it will become life-threatening and lead to respiratory arrest, coma, and death.Overview. Chronic obstructive pulmonary disease (COPD) is a leading cause of death and disability and in the United States. Learn more about the disease and how it affects people nationwide. Print Length: 1 page. Publication Date: September 2022. Language: English.Did you know that you could get a tattoo at Star Wars Celebration? The artists of Ink-Fusion Empire travel to cons to give attendees unforgettable souvenirs. Check out the great ta...Chronic pain is one of the most common reasons adults seek medical care and is often managed with opioid analgesics; however, opioids may cause respiratory depression by suppressing various components of respiration. Respiration is the physiological process that facilitates gas exchange and is mediated through the proper function of and communication among central neural control (respiratory ...N-acetylcysteine (NAC) is the mainstay of therapy for acetaminophen toxicity. NAC has FDA approval for treating potentially hepatotoxic doses of acetaminophen (APAP) and is almost 100% effective if given within 8 hours post-ingestion. NAC is also approved for use in conditions with abnormal viscid or inspissated mucous secretions, such as pneumonia, bronchitis, tracheobronchitis, cystic ...Pulmonary edema can be defined as an abnormal accumulation of extravascular fluid in the lung parenchyma. This process leads to diminished gas exchange at the alveolar level, progressing to potentially causing respiratory failure. Its etiology is either due to a cardiogenic process with the inability to remove sufficient blood away from the pulmonary circulation or non-cardiogenic precipitated ...Respiratory alkalosis is 1 of the 4 basic classifications of blood pH imbalances. Normal human physiological pH is 7.35 to 7.45. A decrease in pH below this range is acidosis, an increase above this range is alkalosis. Respiratory alkalosis is by definition a disease state where the body’s pH is elevated to greater than 7.45 secondary to some respiratory or pulmonary process.[1]Congestive heart failure (CHF), as defined by the American College of Cardiology (ACC) and the American Heart Association (AHA), is "a complex clinical syndrome that results from any structural or functional impairment of ventricular filling or ejection of blood." Ischemic heart disease is the leading cause of death worldwide and also the leading cause of CHF. CHF is a common disorder ...Introduction. Chronic obstructive pulmonary disease (COPD), a common preventable and treatable disease, is characterized by persistent airflow limitation that is usually progressive and that is caused by an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases [].COPD is a major cause of morbidity and mortality worldwide and results in an economic and ...StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. StatPearls [Internet]. ... Table 3. Commonly used maintenance medications in COPD Used with Permission from 2020, Global Initiative for Chronic Obstructive Lung Disease (GOLD), available from www.goldcopd.org, published in Fontana, WI, USA. From: Chronic …Respiratory alkalosis is 1 of the 4 basic classifications of blood pH imbalances. Normal human physiological pH is 7.35 to 7.45. A decrease in pH below this range is acidosis, an increase above this range is alkalosis. Respiratory alkalosis is by definition a disease state where the body's pH is elevated to greater than 7.45 secondary to some respiratory or pulmonary process.[1]Cardiopulmonary resuscitation (CPR) is a collection of interventions performed to provide oxygenation and circulation to the body during cardiac arrest. Our current modern-day approach to this process stemmed from the work of a handful of doctors in the 1950s and has now evolved into the process that will be discussed further here. The most widely accepted guidelines in North America are those ...Upper respiratory tract infections can be defined as self-limited irritation and swelling of the upper airways with associated cough with no proof of pneumonia, lacking a separate condition to account for the patient symptoms, or with no history of COPD/emphysema/chronic bronchitis. [1] Upper respiratory tract infections involve the nose ...Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mm Hg. Carbon dioxide (CO2) is a metabolic product of the many cellular processes within the body to process lipids, carbohydrates, and proteins. There are a host of physiological mechanisms present which are responsible for the moderation of CO2 …Secondary spontaneous pneumothorax is seen more in old-age patients 60-65 years. The incidence of SSP is 6.3 and 2 cases for men and women per 100,000 patients, respectively. The male-to-female ratio is 3:1. COPD has an incidence of 26 pneumothoraces per 100,000 patients. The risk of spontaneous pneumothorax in heavy smokers is 102 times higher ...Syncope is caused by decreased cerebral blood flow leading to transient loss of consciousness and postural tone, associated with spontaneous recovery. Symptoms like dizziness, lightheadedness, diaphoresis, nausea, and visual disturbances may precede it or occur suddenly with none of the above symptoms. Syncope is a symptom described as fainting, blacking out, falling out, or "having a spell ...Acute respiratory distress syndrome (ARDS) is a life-threatening condition characterized by poor oxygenation and non-compliant or "stiff" lungs. The disorder is associated with capillary endothelial injury and diffuse alveolar damage. Once ARDS develops, patients usually have varying degrees of pulmonary artery vasoconstriction and may develop ... As a result, pursed-lip breathing helps support breatThe mechanisms of COPD exacerbation are complex. ReIn chronic obstructive pulmonary disease (COPD), exacerbatio

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Theophylline is a medication used to treat asthma and chronic obstructive pulmonary disease as a second-line drug. It is a bronchodilator. This activity reviews the indications, action, and contraindications for theophylline as a potential agent in treating asthma and chronic obstructive pulmonary disease. This activity will highlight the mechanism of action, adverse event profile ...Chronic obstructive pulmonary disease (COPD) is a common and treatable disease characterized by progressive airflow limitation and tissue destruction. It is associated with structural lung changes due to chronic inflammation from prolonged exposure to noxious particles or gases most commonly cigarette smoke. Chronic …Heart failure (HF) remains a prevailing cause of cardiovascular morbidity and mortality globally despite advancements in therapies and preventive measures. The Centers for Disease Control and Prevention (CDC) estimates that 6.7 million individuals aged 20 or older in the United States are affected by HF. It is anticipated that the prevalence of HF …Diazepam is a benzodiazepine medication that is FDA approved for the management of anxiety disorders, short-term relief of anxiety symptoms, spasticity associated with upper motor neuron disorders, adjunct therapy for muscle spasms, preoperative anxiety relief, management of certain refractory epilepsy patients, and …Emphysema and chronic bronchitis are airflow-limited states contained within the disease state known as chronic obstructive pulmonary disease (COPD). [] Just as asthma is no longer grouped with COPD, the current definition of COPD put forth by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) also no longer distinguishes between emphysema and chronic bronchitis.Pulmonary emphysema is defined as a pathological, permanent dilatation of distal airways (respiratory bronchioles, alveolar ducts, and alveolar sacs) due to the destruction of the walls of the airways without fibrotic changes. Emphysema destroys the essential ventilatory units and interrupts the gas exchange. Functionally, emphysema …Acute bronchitis manifests as an inflammation of these bronchi without evidence of pneumonia and typically affects individuals without underlying chronic obstructive pulmonary disease (COPD). Acute bronchitis is characterized by an acute onset of a persistent cough, with or without sputum production. As a self-limiting condition, it typically ...Lung capacity or total lung capacity (TLC) is the volume of air in the lungs upon the maximum effort of inspiration. Among healthy adults, the average lung capacity is about 6 liters. Age, gender, body composition, and ethnicity are factors affecting the different ranges of lung capacity among individuals. TLC rapid increases from birth to …Pre-Hypertension: SBP 120 to 139 mm Hg and DBP 80 to 89 mm Hg. Stage 1 Hypertension: SBP 140 to 159 mm Hg and DBP 90 to 99 mm Hg. Stage 2 Hypertension: SBP greater than or equal to 160 mm Hg and DBP greater than or equal to 100 mm Hg. The JNC-8 recommendations were exclusively for individuals aged 18 years and above.Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystemic involvement. The condition has several phenotypes, with varying clinical presentations from mild mucocutaneous manifestations to multiorgan and severe central nervous system involvement. Several immunopathogenic pathways play a role in the development of SLE. Hargraves described the lupus erythematosus (LE ...Jan 23, 2023 · Pleurisy is a symptom characterized by localized chest pain caused by a disease-causing inflammation of the pleura. Pleurisy can be caused by a primary pleural disease or secondary to a systemic illness. Hippocrates first described "pleuritis" in the 5 century B.C. as "pain in his side, fever and shivering" accompanied by "orthopnea" and tachypnea."[1] Different types of pleuritis were ...Theophylline is a medication used to treat asthma and chronic obstructive pulmonary disease as a second-line drug. It is a bronchodilator. This activity reviews the indications, action, and contraindications for theophylline as a potential agent in treating asthma and chronic obstructive pulmonary disease. This activity will highlight the mechanism of action, adverse event profile ...Infection Control is a comprehensive guide to the policies and procedures for preventing and minimizing infections in healthcare settings. It covers the history, epidemiology, and evidence-based practices of infection control programs, as well as the role of nurses and other healthcare professionals in implementing them. Learn how to reduce the risk of hospital-acquired infections and improve ...According to the lay press, 75% of Americans are chronically dehydrated. While this is not supported by medical literature, dehydration is common in elderly patients. It has been reported to occur in 17% to 28% of older adults in the United States.[1] Dehydration is a frequent cause of hospital admission. It can cause morbidity and mortality on its own and complicates many medical conditions ...Inhalation anesthetics (nitrous oxide, halothane, isoflurane, desflurane, sevoflurane, most commonly used agents in practice today) are used for induction and maintenance of general anesthesia in the operating room. This review is a general overview of inhalation anesthetic agents. Inhalation anesthetic agents are medications primarily used in the operating room to provide general anesthesia ...Asthma is becoming a more prevalent disease since the early 1990s. From 1982 to 1992, the rate of asthma jumped from 34.7 to 49.4 per thousand.[1] The prevalence of asthma in the USA is around 8%.[2] There also has been some mixed trends around the world where different countries have either had increasing cases or have been stagnant.[3] In children, asthma is presented predominantly in males ...StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. StatPearls [Internet]. Show details ... COPD usually start with a pressure of 5 cm water versus those with congestive heart failure (CHF), severe pneumonia and pulmonary edema due to near-drownings at 10 cm water. With these levels, the work of breathing can be ...Adenosine is a purine nucleoside base, most commonly recognized with the molecule adenosine triphosphate, or ATP, and is used thoroughly throughout the entire body in general metabolism. [6] Adenosine’s use as a pharmacological drug works through receptors called purinergic adenosine receptors found throughout the body.In this retrospective study, 34 patients (aged 20-59 years) underwent ACL reconstruction using hamstring tendon autograft with 2 different incision techniques on the SF.Pulmonary hemorrhage, also referred to as massive hemoptysis, is a potentially life-threatening condition involving bleeding from the pulmonary or bronchial vasculature, of which the usual culprit is the higher pressure bronchial system.[1] Prior definition of pulmonary hemorrhage focused on classifications based on the rate and amount of overall blood loss which can be difficult to quantify ...Emphysema symptoms start when the walls of tiny air sacs (alveoli) in the lungs become damaged, so less air gets in and out of the lungs. This results in low oxygen levels and makes you feel tired ...Chronic obstructive pulmonary disease (COPD) is a common co-morbidity and cause of new complaints. Rapid recognition, assessment, and treatment are paramount to patient outcomes. Gone are the days of definitive …Bilirubin is an important metabolite of heme (ferroprotoporphyrin IX), a coordination complex coordinating iron in various proteins. It is a potentially toxic substance. However, the body has developed mechanisms for its safe detoxification and disposition. Bilirubin and its metabolites also provide a distinctive yellow color to bile and stool and, …May 1, 2024 · Rene Laënnec's invention of the stethoscope in the early 1800s paved the way for the clinical examination of the lungs. The lung exam is a standard approach for comprehensive and focused physical examinations in patients. Due to their proximity to vital structures such as the heart, great vessels, esophagus, and diaphragm, a careful examination of the lungs can offer valuable insights for ...Respiratory alkalosis is 1 of the 4 basic classifications of blood pH imbalances. Normal human physiological pH is 7.35 to 7.45. A decrease in pH below this range is acidosis, an increase above this range is alkalosis. Respiratory alkalosis is by definition a disease state where the body's pH is elevated to greater than 7.45 secondary to some respiratory or pulmonary process.[1]Discuss interprofessional team strategies for improving care coordination and communication to advance chronic obstructive pulmonary disease (COPD) and improve outcomes. Disclosures StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that ...Nosocomial pneumonia or hospital-acquired pneumoThe mechanisms of COPD exacerbation are comp

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Supplemental oxygen therapy is one of the more commonly prescribed interventions used by physicians when caring for hypoxic patients acutely. This supplementation often takes the form of a low-flow nasal cannula (LFNC). However, there are limitations to this supplemental oxygen intervention. A traditional nasal cannula can only effectively provide only up to 4 to 6 liters per minute of ...Exacerbation of COPD. An exacerbation (ex-zass-cer-bay-shun) of Chronic Obstructive Pulmonary Disease (COPD) is a worsening or “flare up” of your COPD symptoms. In many cases an exacerbation is caused by an infection in the lungs, but in some cases, the cause is never known. The inflammation (irritation and swelling) in the lungs during and ...Capillary refill time (CRT) is a useful and rapid metric in determining the intravascular volume status of ill patients, particularly those with conditions that arise or result from hypovolemia. Examples of these pathologic states include but are not limited to hypo and hyperthermia, all forms of shock, hemorrhage, loss of plasma volume in ...Excerpt. Pulmonary capillary wedge pressure (PCWP) is frequently used to assess left ventricular filling, represent left atrial pressure, and assess mitral valve function. It is measured by inserting a balloon-tipped, multi-lumen catheter (Swan-Ganz catheter) into a central vein and advancing the catheter into a branch of the pulmonary artery.COPD is characterized by airflow limitation and chronic respiratory symptoms, including cough and shortness of breath. It affects around 15 million people in the United States and costs more than ...Nitric oxide is a medication used to manage and treat hypoxic respiratory failure or persistent pulmonary hypertension in newborns. It is in the miscellaneous respiratory agent class of drugs. Its administration in the clinical scenario as an inhalant (iNO) for adjunctive rescue therapy and improved oxygenation of persistent pulmonary hypertension of newborns (PPHN) and acute respiratory ...111 Indium White Blood Cell Scan. 17-Hydroxylase Deficiency. 21-Hydroxylase Deficiency. 24-Hour Urine Collection. 24-Hour Urine Testing for Nephrolithiasis: Interpretation and Treatment Guidelines. 2-Octyl Cyanoacrylate. 3,4-Methylenedioxymethamphetamine (MDMA) Toxicity. 3-3-2 Rule.Aspiration pneumonia is an infectious pulmonary condition triggered by entering bacteria-rich oropharyngeal fluids into the lower respiratory tract. The aspirated fluid may contain oropharyngeal secretions, particulate matter, or gastric content. Aspiration pneumonia manifests across various clinical contexts and primarily affects older adults. It poses significant risks of morbidity and ...Chronic bronchitis is a type of chronic obstructive pulmonary disease (COPD) that is defined as a productive cough of more than 3 months occurring within a span of 2 years. Patients typically present with chronic productive cough, malaise, and symptoms of excessive coughing, such as chest or abdominal pain. This activity reviews the evaluation ...A pneumothorax is a collection of air outside the lung but within the pleural cavity. It occurs when air accumulates between the parietal and visceral pleurae inside the chest. The air accumulation can apply pressure on the lung and make it collapse. The degree of collapse determines the clinical presentation of pneumothorax.The mechanisms of COPD exacerbation are complex. Respiratory viruses (in particular rhinovirus) and bacteria play a major role in the causative etiology of COPD exacerbations. In some patients, noninfective environmental factors may also be important. Data recently published from a large observational study identified a phenotype of patients ...COPD is a progressive disease that causes less air to flow through the airways and impacts breathing. It can cause symptoms that include shortness of breath, chest discomfort, and coughing ...Chronic obstructive pulmonary disease (COPD) is one of the leading global causes of morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily caused by cigarette smoke (CS). CS exposure causes an imbalance favoring pro- over antioxidants (oxidative stress), leading to transcription factor activation and increased expression of inflammatory mediators and proteases ...Jun 26, 2023 · Phosphodiesterase inhibitors (PDE inhibitors) are a class of agents acting on phosphodiesterase enzymes. They are FDA approved to manage chronic obstructive pulmonary disease, erectile dysfunction, pulmonary arterial hypertension, acute decompensated heart failure, psoriasis, psoriatic arthritis, atopic dermatitis, and neonatal apnea.Magnesium use is indicated for a variety of diseases. This is due to the variety of effects magnesium has within the body. Administration of magnesium can be divided into FDA versus non-FDA approved. Also, magnesium is commonly used in over-the-counter products. This activity will highlight the mechanism of action, adverse event …Pneumothorax is air collection in the pleural space, resulting in lung collapse from positive pleural pressure. Tension pneumothorax occurs when pleural pressure is transmitted to the mediastinum (see Image. Left-Sided Tension Pneumothorax Radiograph). This uncommon condition has a malignant course and might result in death if left untreated.[1][2] Tension pneumothorax may arise in the ...The partial pressure of carbon dioxide (PCO2) is the measure of carbon dioxide within arterial or venous blood. It often serves as a marker of sufficient alveolar ventilation within the lungs. Generally, under normal physiologic conditions, the value of PCO2 ranges between 35 to 45 mmHg, or 4.7 to 6.0 kPa. Typically the measurement of PCO2 is ...Acute exacerbations have an important impact on health status, disease progression, and prognosis of patients with COPD.1 The frequency and severity of exacerbations substantially drive the associated high costs and burden.1 Therefore it is key in the treatment of patients with COPD to prevent exacerbations or their relapse and to promote quick recovery with bronchodilators, antibiotics, and ...Hyperlipidemia is a condition that incorporates various genetic and acquired disorders that describe elevated lipid levels within the human body. Hyperlipidemia is extremely common, especially in the Western hemisphere, but also throughout the world. Alternatively, a more objective definition describes hyperlipidemia as low-density lipoprotein (LDL), total cholesterol, triglyceride levels, or ... Pulmonary embolism (PE) is a treatable disease